Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition

The PIM family of proteins encodes serine/threonine kinases with important roles in protein synthesis and cancer cell metabolism. In glioblastoma (GBM) cell lines, siRNA-mediated knockdown of PIM kinases or pharmacological inhibition of PIM kinases by SGI-1776 or AZD-1208 results in reduced phosphor...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Iqbal, Asneha, Eckerdt, Frank, Bell, Jonathan, Nakano, Ichiro, Giles, Francis J., Cheng, Shi-Yuan, Lulla, Rishi R., Goldman, Stewart, Platanias, Leonidas C.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078085/
https://ncbi.nlm.nih.gov/pubmed/27120806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8899
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars