Characterization of SR 121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist.

SR 121463A, a potent and selective, orally active, nonpeptide vasopressin V2 receptor antagonist, has been characterized in several in vitro and in vivo models. This compound displayed highly competitive and selective affinity for V2 receptors in rat, bovine and human kidney (0.6 < or = Ki [nM] &...

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Main Authors: Serradeil-Le Gal, C, Lacour, C, Valette, G, Garcia, G, Foulon, L, Galindo, G, Bankir, L, Pouzet, B, Guillon, G, Barberis, C, Chicot, D, Jard, S, Vilain, P, Garcia, C, Marty, E, Raufaste, D, Brossard, G, Nisato, D, Maffrand, J P, Le Fur, G
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507737/
https://ncbi.nlm.nih.gov/pubmed/8981918
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