Endothelin action in rat liver. Receptors, free Ca2+ oscillations, and activation of glycogenolysis.

High affinity binding sites for endothelin (ET) were identified on rat liver plasma membranes. Binding of 125I-ET-1 with its site was specific, saturable, and time dependent (kobs = 0.019 +/- 0.001 min-1), but dissociation of receptor-bound ligand was minimal. A single class of high affinity binding...

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Main Authors: Serradeil-Le Gal, C, Jouneaux, C, Sanchez-Bueno, A, Raufaste, D, Roche, B, Préaux, A M, Maffrand, J P, Cobbold, P H, Hanoune, J, Lotersztajn, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295008/
https://ncbi.nlm.nih.gov/pubmed/1845867
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