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Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism

The mechanistic target of rapamycin complex 1 (mTORC1) coordinates cell growth with its nutritional, hormonal, energy, and stress status. Amino acids are critical regulators of mTORC1 that permit other inputs to mTORC1 activity. However, the roles of individual amino acids and their interactions in...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Dyachok, Julia, Earnest, Svetlana, Iturraran, Erica N., Cobb, Melanie H., Ross, Elliott M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077182/
https://ncbi.nlm.nih.gov/pubmed/27587390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732511
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