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Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism

The mechanistic target of rapamycin complex 1 (mTORC1) coordinates cell growth with its nutritional, hormonal, energy, and stress status. Amino acids are critical regulators of mTORC1 that permit other inputs to mTORC1 activity. However, the roles of individual amino acids and their interactions in...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Dyachok, Julia, Earnest, Svetlana, Iturraran, Erica N., Cobb, Melanie H., Ross, Elliott M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077182/
https://ncbi.nlm.nih.gov/pubmed/27587390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732511
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