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Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules
Endonuclease V (EndoV) is an enzyme with specificity for inosines in nucleic acids. Whereas the bacterial homologs are active on both DNA and RNA, the mammalian variants only cleave RNA, at least when assayed with recombinant proteins. Here we show that ectopically expressed, as well as endogenously...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5076846/ https://ncbi.nlm.nih.gov/pubmed/27573237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.730911 |
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