Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the extent of population differences in immune responses and their genetic and evolutionary determinants remain undefined. Here, we characterized, using RNA sequencing, the transcriptional response of primary monoc...

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Publicado en:Cell
Main Authors: Quach, Hélène, Rotival, Maxime, Pothlichet, Julien, Loh, Yong-Hwee Eddie, Dannemann, Michael, Zidane, Nora, Laval, Guillaume, Patin, Etienne, Harmant, Christine, Lopez, Marie, Deschamps, Matthieu, Naffakh, Nadia, Duffy, Darragh, Coen, Anja, Leroux-Roels, Geert, Clément, Frederic, Boland, Anne, Deleuze, Jean-François, Kelso, Janet, Albert, Matthew L., Quintana-Murci, Lluis
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075285/
https://ncbi.nlm.nih.gov/pubmed/27768888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.024
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