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Defining the genetic and evolutionary architecture of alternative splicing in response to infection

Host and environmental factors contribute to variation in human immune responses, yet the genetic and evolutionary drivers of alternative splicing in response to infection remain largely uncharacterised. Leveraging 970 RNA-sequencing profiles of resting and stimulated monocytes from 200 individuals...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rotival, Maxime, Quach, Hélène, Quintana-Murci, Lluis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459842/
https://ncbi.nlm.nih.gov/pubmed/30975994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09689-7
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