Population variation in miRNAs and isomiRs and their impact on human immunity to infection

BACKGROUND: MicroRNAs (miRNAs) are key regulators of the immune system, yet their variation and contribution to intra- and inter-population differences in immune responses is poorly characterized. RESULTS: We generate 977 miRNA-sequencing profiles from primary monocytes from individuals of African a...

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Vydáno v:Genome Biol
Hlavní autoři: Rotival, Maxime, Siddle, Katherine J., Silvert, Martin, Pothlichet, Julien, Quach, Hélène, Quintana-Murci, Lluis
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391576/
https://ncbi.nlm.nih.gov/pubmed/32731901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02098-w
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