Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the extent of population differences in immune responses and their genetic and evolutionary determinants remain undefined. Here, we characterized, using RNA sequencing, the transcriptional response of primary monoc...

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Gepubliceerd in:Cell
Hoofdauteurs: Quach, Hélène, Rotival, Maxime, Pothlichet, Julien, Loh, Yong-Hwee Eddie, Dannemann, Michael, Zidane, Nora, Laval, Guillaume, Patin, Etienne, Harmant, Christine, Lopez, Marie, Deschamps, Matthieu, Naffakh, Nadia, Duffy, Darragh, Coen, Anja, Leroux-Roels, Geert, Clément, Frederic, Boland, Anne, Deleuze, Jean-François, Kelso, Janet, Albert, Matthew L., Quintana-Murci, Lluis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075285/
https://ncbi.nlm.nih.gov/pubmed/27768888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.024
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