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Complement C5 Inhibition Reduces T Cell-Mediated Allograft Vasculopathy Caused by Both Alloantibody and Ischemia Reperfusion Injury in Humanized Mice

Allograft vasculopathy (AV) is characterized by diffuse stenoses in the vasculature of solid organ transplants. Previously, we developed two humanized models showing that alloantibody and ischemia reperfusion injury (IRI) exacerbated T cell-mediated AV in human arterial xenografts in vivo. Here we e...

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書誌詳細
出版年:Am J Transplant
主要な著者: Qin, Lingfeng, Li, Guangxin, Kirkiles-Smith, Nancy, Clark, Pamela, Fang, Caodi, Wang, Yi, Yu, Zhao-Xue, Devore, Denise, Tellides, George, Pober, Jordan S, Jane-wit, Dan
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075274/
https://ncbi.nlm.nih.gov/pubmed/27104811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13834
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