Complement C5 Inhibition Reduces T Cell-Mediated Allograft Vasculopathy Caused by Both Alloantibody and Ischemia Reperfusion Injury in Humanized Mice

Allograft vasculopathy (AV) is characterized by diffuse stenoses in the vasculature of solid organ transplants. Previously, we developed two humanized models showing that alloantibody and ischemia reperfusion injury (IRI) exacerbated T cell-mediated AV in human arterial xenografts in vivo. Here we e...

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Detaylı Bibliyografya
Yayımlandı:Am J Transplant
Asıl Yazarlar: Qin, Lingfeng, Li, Guangxin, Kirkiles-Smith, Nancy, Clark, Pamela, Fang, Caodi, Wang, Yi, Yu, Zhao-Xue, Devore, Denise, Tellides, George, Pober, Jordan S, Jane-wit, Dan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075274/
https://ncbi.nlm.nih.gov/pubmed/27104811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13834
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