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Activation of endogenous deltaF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition.

Many heterologously expressed mutants of the cystic fibrosis transmembrane conductance regulator (CFTR) exhibit residual chloride channel activity that can be stimulated by agonists of the adenylate cyclase/protein kinase A pathway. Because of clinical implications for cystic fibrosis of activating...

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Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Kelley, T J, Al-Nakkash, L, Cotton, C U, Drumm, M L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 1996
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507457/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755664/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118819
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