Chemical chaperones correct the mutant phenotype of the ΔF508 cystic fibrosis transmembrane conductance regulator protein

Mutations in the cystic fibriosis transmembrane conductance regulator protein (CFTR) often result in a failure of the protein to be propely processed at the level of the endoplasmic reticulum (ER) and subsequently transported to the plasma membrane. The folding defect associated with the most common...

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Detaylı Bibliyografya
Yayımlandı:Cell Stress Chaperones
Asıl Yazarlar: Brown, C. Randell, Hong-Brown, Ly Q., Biwersi, Joachim, Verkman, A. S., Welch, William. J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 1996
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248464/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9222597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1379/1466-1268(1996)001<0117:ccctmp>2.3.co;2
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