Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

Adeno-associated virus (AAV) vectors expressing the normal cystic fibrosis transmembrane conductance regulator (CFTR) cDNA complement the cystic fibrosis (CF) defect in vitro. Unlike other DNA virus vectors, AAV is a stably integrating virus, which could make possible long-term in vivo complementati...

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Detalhes bibliográficos
Main Authors: Flotte, T R, Afione, S A, Conrad, C, McGrath, S A, Solow, R, Oka, H, Zeitlin, P L, Guggino, W B, Carter, B J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47827/
https://ncbi.nlm.nih.gov/pubmed/7504271
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