Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

Adeno-associated virus (AAV) vectors expressing the normal cystic fibrosis transmembrane conductance regulator (CFTR) cDNA complement the cystic fibrosis (CF) defect in vitro. Unlike other DNA virus vectors, AAV is a stably integrating virus, which could make possible long-term in vivo complementati...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Flotte, T R, Afione, S A, Conrad, C, McGrath, S A, Solow, R, Oka, H, Zeitlin, P L, Guggino, W B, Carter, B J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10613
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