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Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase.
Mitochondria were isolated from skin fibroblast cultures derived from healthy individuals (controls) and from a group patients with complex I (NADH-CoQ reductase) deficiency of the mitochondrial respiratory chain. The complex I deficient patients included those with fatal infantile lactic acidosis (...
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| Udgivet i: | J Clin Invest |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118798 |
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