Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice.

Manganese superoxide dismutase (SOD2) converts superoxide to oxygen plus hydrogen peroxide and serves as the primary defense against mitochondrial superoxide. Impaired SOD2 activity in humans has been associated with several chronic diseases, including ovarian cancer and type I diabetes, and SOD2 ov...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lebovitz, R M, Zhang, H, Vogel, H, Cartwright, J, Dionne, L, Lu, N, Huang, S, Matzuk, M M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38506/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9782
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