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Efficacy of adoptive T cell therapy is improved by treatment with the antioxidant N-acetyl cysteine, which limits activation-induced T cell death
While adoptive transfer of autologous tumor antigen-specific T cell immunotherapy can produce remarkable clinical efficacy, most patients do not achieve durable complete responses. We hypothesized that reducing susceptibility of T cells to activation-induced cell death (AICD), which increases during...
Enregistré dans:
| Publié dans: | Cancer Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5074089/ https://ncbi.nlm.nih.gov/pubmed/27742673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0587 |
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