Increased gene expression of Alzheimer disease beta-amyloid precursor protein in senescent cultured fibroblasts.

The pathological hallmark of Alzheimer disease is the accumulation of neurofibrillary tangles and neuritic plaques in the brains of patients. Plaque cores contain a 4- to 5-kDa amyloid beta-protein fragment which is also found in the cerebral blood vessels of affected individuals. Since amyloid depo...

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Detaylı Bibliyografya
Asıl Yazarlar: Adler, M J, Coronel, C, Shelton, E, Seegmiller, J E, Dewji, N N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC50738/
https://ncbi.nlm.nih.gov/pubmed/1702541
Etiketler: Etiketle
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