Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein.

Extracellular deposition of the beta/A4 amyloid peptide is a characteristic feature of the brain in patients with Alzheimer disease. beta/A4 amyloid is derived from the amyloid precursor protein (APP), an integral membrane protein that exists as three major isoforms (APP695, APP751, and APP770). Sec...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Caporaso, G L, Gandy, S E, Buxbaum, J D, Ramabhadran, T V, Greengard, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3055
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