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A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme Activation
RNA enzymes serve as a potentially powerful platform from which to design catalysts and engineer new biotechnology. A fundamental understanding of these systems provides insight to guide design. The hepatitis delta virus ribozyme (HDVr) is a small, self-cleaving RNA motif widely distributed in natur...
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| Published in: | ACS Catal |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072530/ https://ncbi.nlm.nih.gov/pubmed/27774349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.5b02158 |
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