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A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme Activation
RNA enzymes serve as a potentially powerful platform from which to design catalysts and engineer new biotechnology. A fundamental understanding of these systems provides insight to guide design. The hepatitis delta virus ribozyme (HDVr) is a small, self-cleaving RNA motif widely distributed in natur...
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Gepubliceerd in: | ACS Catal |
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Hoofdauteurs: | , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072530/ https://ncbi.nlm.nih.gov/pubmed/27774349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.5b02158 |
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