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Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle.

We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-release channels. Imperatoxin inhibitor has a M(r) of approximately 10,500, inhibit...

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Bibliographic Details
Main Authors: Valdivia, H H, Kirby, M S, Lederer, W J, Coronado, R
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC50723/
https://ncbi.nlm.nih.gov/pubmed/1334561
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