Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle.

We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-release channels. Imperatoxin inhibitor has a M(r) of approximately 10,500, inhibits [3H]ryanodine bind...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Valdivia, H H, Kirby, M S, Lederer, W J, Coronado, R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1992
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1334561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12185
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