Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle.

We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-release channels. Imperatoxin inhibitor has a M(r) of approximately 10,500, inhibits [3H]ryanodine bind...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Valdivia, H H, Kirby, M S, Lederer, W J, Coronado, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1334561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.12185
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