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Ca2+-Releasing Effect of Cerivastatin on the Sarcoplasmic Reticulum of Mouse and Rat Skeletal Muscle Fibers

ABSTRACT: We analyzed the effect of HMG-CoA reductase inhibitors on Ca2+ release from the sarcoplasmic reticulum (SR) using chemically skinned skeletal muscle fibers from the mouse and the rat. Cerivastatin (>20 μM) released Ca2+ from the SR, while pravastatin showed only a little effect. The rates...

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Bibliografiske detaljer
Principais autores: Ryotaku Inoue, Mitsuo Tanabe, Keita Kono, Kei Maruyama, Takaaki Ikemoto, Makoto Endo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2003-01-01
Serier:Journal of Pharmacological Sciences
Online adgang:http://www.sciencedirect.com/science/article/pii/S1347861319325770
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