Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in Apc(Min) Mice

Constitutive β-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous polyposis. Mice carrying Apc mutations in their germ line (Apc(Min)) develop intestinal adenomas. Here, the...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Hulit, James, Wang, Chenguang, Li, Zhiping, Albanese, Chris, Rao, Mahadev, Di Vizio, Dolores, Shah, Salimuddin, Byers, Stephen W., Mahmood, Radma, Augenlicht, Leonard H., Russell, Robert, Pestell, Richard G.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2004
Teme:
Cell Growth and Development
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.17.7598-7611.2004
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