Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in Apc(Min) Mice

Constitutive β-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous polyposis. Mice carrying Apc mutations in their germ line (Apc(Min)) develop intestinal adenomas. Here, the...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Hulit, James, Wang, Chenguang, Li, Zhiping, Albanese, Chris, Rao, Mahadev, Di Vizio, Dolores, Shah, Salimuddin, Byers, Stephen W., Mahmood, Radma, Augenlicht, Leonard H., Russell, Robert, Pestell, Richard G.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.17.7598-7611.2004
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