Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in Apc(Min) Mice

Constitutive β-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous polyposis. Mice carrying Apc mutations in their germ line (Apc(Min)) develop intestinal adenomas. Here, the...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Hulit, James, Wang, Chenguang, Li, Zhiping, Albanese, Chris, Rao, Mahadev, Di Vizio, Dolores, Shah, Salimuddin, Byers, Stephen W., Mahmood, Radma, Augenlicht, Leonard H., Russell, Robert, Pestell, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2004
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.17.7598-7611.2004
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