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Separation of Insulin Signaling into Distinct GLUT4 Translocation and Activation Steps
GLUT4 (glucose transporter 4) plays a pivotal role in insulin-induced glucose uptake to maintain normal blood glucose levels. Here, we report that a cell-permeable phosphoinositide-binding peptide induced GLUT4 translocation to the plasma membrane without inhibiting IRAP (insulin-responsive aminopep...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC507006/ https://ncbi.nlm.nih.gov/pubmed/15314166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7567-7577.2004 |
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