Insulin-regulated Glut4 Translocation: MEMBRANE PROTEIN TRAFFICKING WITH SIX DISTINCTIVE STEPS

The trafficking kinetics of Glut4, the transferrin (Tf) receptor, and LRP1 were quantified in adipocytes and undifferentiated fibroblasts. Six steps were identified that determine steady state cell surface Glut4: (i) endocytosis, (ii) degradation, (iii) sorting, (iv) sequestration, (v) release, and...

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Detalhes bibliográficos
Main Authors: Brewer, Paul Duffield, Habtemichael, Estifanos N., Romenskaia, Irina, Mastick, Cynthia Corley, Coster, Adelle C. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067164/
https://ncbi.nlm.nih.gov/pubmed/24778187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555714
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