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Insulin-regulated Glut4 Translocation: MEMBRANE PROTEIN TRAFFICKING WITH SIX DISTINCTIVE STEPS

The trafficking kinetics of Glut4, the transferrin (Tf) receptor, and LRP1 were quantified in adipocytes and undifferentiated fibroblasts. Six steps were identified that determine steady state cell surface Glut4: (i) endocytosis, (ii) degradation, (iii) sorting, (iv) sequestration, (v) release, and...

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Autori principali: Brewer, Paul Duffield, Habtemichael, Estifanos N., Romenskaia, Irina, Mastick, Cynthia Corley, Coster, Adelle C. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067164/
https://ncbi.nlm.nih.gov/pubmed/24778187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555714
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