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SKIP Negatively Regulates Insulin-Induced GLUT4 Translocation and Membrane Ruffle Formation
Skeletal muscle and kidney enriched inositol phosphatase (SKIP) is an inositol polyphosphate 5-phosphatase that hydrolyzes phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P(3)] to downregulate intracellular levels. In this study, we show that SKIP inhibits phosphoinositide 3-kinase signaling in i...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141139/ https://ncbi.nlm.nih.gov/pubmed/12556481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1209-1220.2003 |
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