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Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis

Lipopolysaccharide (LPS) signaling is critical for the innate immune response to gram-negative bacteria. Here, evidence is presented for LPS stimulation of sphingosine kinase (SPK) in the RAW 264.7 murine macrophage cell line and rat primary hepatic macrophages (HMs). LPS treatment of RAW 264.7 cell...

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Bibliografiska uppgifter
Huvudupphovsmän: Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC507005/
https://ncbi.nlm.nih.gov/pubmed/15314148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7359-7369.2004
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