Sphingosine Kinase Protects Lipopolysaccharide-Activated Macrophages from Apoptosis

Lipopolysaccharide (LPS) signaling is critical for the innate immune response to gram-negative bacteria. Here, evidence is presented for LPS stimulation of sphingosine kinase (SPK) in the RAW 264.7 murine macrophage cell line and rat primary hepatic macrophages (HMs). LPS treatment of RAW 264.7 cell...

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Detalles Bibliográficos
Main Authors: Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC507005/
https://ncbi.nlm.nih.gov/pubmed/15314148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7359-7369.2004
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