Lipopolysaccharide-Induced Activation of β2-Integrin Function in Macrophages Requires Irak Kinase Activity, p38 Mitogen- Activated Protein Kinase, and the Rap1 GTPase

Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, is a potent activator of macrophages. Besides inducing many transcriptional pathways, LPS also elicits rapid morphological changes such as cell spreading. Here we have investigated the signaling pathway that contr...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Schmidt, Anja, Caron, Emmanuelle, Hall, Alan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86592/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134332/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.438-448.2001
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