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Lipopolysaccharide-Induced Activation of β2-Integrin Function in Macrophages Requires Irak Kinase Activity, p38 Mitogen- Activated Protein Kinase, and the Rap1 GTPase

Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, is a potent activator of macrophages. Besides inducing many transcriptional pathways, LPS also elicits rapid morphological changes such as cell spreading. Here we have investigated the signaling pathway that contr...

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Bibliografske podrobnosti
Main Authors: Schmidt, Anja, Caron, Emmanuelle, Hall, Alan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC86592/
https://ncbi.nlm.nih.gov/pubmed/11134332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.438-448.2001
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