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Saccharomyces cerevisiae Srs2 DNA Helicase Selectively Blocks Expansions of Trinucleotide Repeats

Trinucleotide repeats (TNRs) undergo frequent mutations in families afflicted with certain neurodegenerative disorders and in model organisms. TNR instability is modulated both by the repeat tract itself and by cellular proteins. Here we identified the Saccharomyces cerevisiae DNA helicase Srs2 as a...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Bhattacharyya, Saumitri, Lahue, Robert S.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.17.7324-7330.2004
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