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TGF-β induces p53/Smads complex formation in the PAI-1 promoter to activate transcription
Transforming growth factor β (TGF-β) signaling facilitates tumor development during the advanced stages of tumorigenesis, but induces cell-cycle arrest for tumor suppression during the early stages. However, the mechanism of functional switching of TGF-β is still unknown, and it is unclear whether i...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069723/ https://ncbi.nlm.nih.gov/pubmed/27759037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35483 |
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