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Optimization of a novel series of pyranopyridine RND efflux pump inhibitors
The rise of multidrug resistant (MDR) Gram-negative pathogens complicates our ability to treat bacterial infections with antibiotics. MDR efflux pumps play a major role in the acquisition and expression of the MDR phenotype. The major MDR efflux pumps in the Gram-negative pathogens are the resistanc...
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| Publicado no: | Curr Opin Microbiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069128/ https://ncbi.nlm.nih.gov/pubmed/27232955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2016.05.007 |
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