Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli

Members of the resistance-nodulation-division (RND) family of efflux pumps, such as AcrAB-TolC of Escherichia coli, play major roles in multidrug resistance (MDR) in Gram-negative bacteria. A strategy for combating MDR is to develop efflux pump inhibitors (EPIs) for use in combination with an antiba...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Opperman, Timothy J., Kwasny, Steven M., Kim, Hong-Suk, Nguyen, Son T., Houseweart, Chad, D'Souza, Sanjay, Walker, Graham C., Peet, Norton P., Nikaido, Hiroshi, Bowlin, Terry L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910843/
https://ncbi.nlm.nih.gov/pubmed/24247144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01866-13
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