Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli

Members of the resistance-nodulation-division (RND) family of efflux pumps, such as AcrAB-TolC of Escherichia coli, play major roles in multidrug resistance (MDR) in Gram-negative bacteria. A strategy for combating MDR is to develop efflux pump inhibitors (EPIs) for use in combination with an antiba...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Opperman, Timothy J., Kwasny, Steven M., Kim, Hong-Suk, Nguyen, Son T., Houseweart, Chad, D'Souza, Sanjay, Walker, Graham C., Peet, Norton P., Nikaido, Hiroshi, Bowlin, Terry L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910843/
https://ncbi.nlm.nih.gov/pubmed/24247144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01866-13
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky