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Mechanisms of RND Multidrug Efflux Pumps

RND (Resistance-Nodulation-Division) family transporters are widespread especially among Gram-negative bacteria, and catalyze the active efflux of many antibiotics and chemotherapeutic agents. They have very large periplasmic domains, and form tripartite complexes with outer membrane channels and pe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Nikaido, Hiroshi, Takatsuka, Yumiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696896/
https://ncbi.nlm.nih.gov/pubmed/19026770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.10.004
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