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Covalently Linked Trimer of the AcrB Multidrug Efflux Pump Provides Support for the Functional Rotating Mechanism

Escherichia coli AcrB is a proton motive force-dependent multidrug efflux transporter that recognizes multiple toxic chemicals having diverse structures. Recent crystallographic studies of the asymmetric trimer of AcrB suggest that each protomer in the trimeric assembly goes through a cycle of confo...

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Detalhes bibliográficos
Main Authors: Takatsuka, Yumiko, Nikaido, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648379/
https://ncbi.nlm.nih.gov/pubmed/19060146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01441-08
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