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Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library

The addition of palmitoyl moieties to proteins regulates their membrane targeting, subcellular localization, and stability. Dysregulation of the enzymes which catalyzed the palmitoyl addition and/or the substrates of these enzymes have been linked to cancer, cardiovascular, and neurological disorder...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Comb Chem High Throughput Screen
Päätekijät: Hamel, Laura D., Lenhart, Brian J., Mitchell, David A., Santos, Radleigh G., Giulianotti, Marc A., Deschenes, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Bentham Science Publishers 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068503/
https://ncbi.nlm.nih.gov/pubmed/27009891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1386207319666160324123844
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