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Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library
The addition of palmitoyl moieties to proteins regulates their membrane targeting, subcellular localization, and stability. Dysregulation of the enzymes which catalyzed the palmitoyl addition and/or the substrates of these enzymes have been linked to cancer, cardiovascular, and neurological disorder...
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| Publicado no: | Comb Chem High Throughput Screen |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068503/ https://ncbi.nlm.nih.gov/pubmed/27009891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1386207319666160324123844 |
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