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Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis
The focal nature of atherosclerotic lesions suggests an important role of local hemodynamic environment. Recent studies have demonstrated significant roles of Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) in mediating mechanotransduction and vascular homeo...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068257/ https://ncbi.nlm.nih.gov/pubmed/27671657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613121113 |
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