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Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1

There is increasing evidence that epigenetic mechanisms such as changes in DNA methylation and histone modification play an important role in regulating cellular functions in physiological and pathophysiological states. We investigated the effects of hemodynamic force disturbance, one of the risk fa...

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Detalhes bibliográficos
Main Authors: Zhou, Jing, Li, Yi-Shuan, Wang, Kuei-Chun, Chien, Shu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036703/
https://ncbi.nlm.nih.gov/pubmed/24883126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-014-0325-z
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