The Mammalian Target of Rapamycin and DNA methyltransferase 1 axis mediates vascular endothelial dysfunction in response to disturbed flow

The earliest atherosclerotic lesions preferentially develop in arterial regions experienced disturbed blood flow, which induces endothelial expression of pro-atherogenic genes and the subsequent endothelial dysfunction. Our previous study has demonstrated an up-regulation of DNA methyltransferase 1...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Yun-Peng, Huang, Yi-Tao, Huang, Tse-Shun, Pang, Wei, Zhu, Juan-Juan, Liu, Yue-Feng, Tang, Run-Ze, Zhao, Chuan-Rong, Yao, Wei-Juan, Li, Yi-Shuan, Chien, Shu, Zhou, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678172/
https://ncbi.nlm.nih.gov/pubmed/29118325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15387-5
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