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A novel regulatory element (E77) isolated from CHO‐K1 genomic DNA enhances stable gene expression in Chinese hamster ovary cells

Vectors flanked by regulatory DNA elements have been used to generate stable cell lines with high productivity and transgene stability; however, regulatory elements in Chinese hamster ovary (CHO) cells, which are the most widely used mammalian cells in biopharmaceutical production, are still poorly...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biotechnol J
Prif Awduron: Kang, Shin‐Young, Kim, Yeon‐Gu, Kang, Seunghee, Lee, Hong Weon, Lee, Eun Gyo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: WILEY‐VCH Verlag 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067685/
https://ncbi.nlm.nih.gov/pubmed/26762773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201500464
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